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In order to make those data accessible, the individual data sets need to be collected, reviewed and harmonized in a number of aspects, including the systematic performance of plausibility checks, the minimization of error, the adaptation of the sequencing ranges and the standardized presentation (alignment and annotation) of the mtDNA haplotypes.
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For convenience of presentation our alignment does not include the duplicated exons 9c, 9d and 9e (+9c; +9c-9e) that were found in three species only.
In addition, the interactive capability of graphical presentation of sequence alignments and selecting and storing all sequences under a selected node in the resulting phylogenetic tree by clicking the node is also provided.
The important difference between the intervention and control conditions is the use of structural, progressive, and hierarchical alignment in the presentation of magnitude information.
Additional file 10: Multiple alignment and LOGO presentation.
Hence, temporal alignment of stimulus presentation and motor activity may have been critical for the improved performance.
SvH implicated in the coordination of the study, involved in the treatment of patients included in the study, participated to sequence alignment and data presentation.
All alignments were exported from MEGA5 in fasta format, and imported into CLUTALX 2.09 to create color-coded PDF alignment files for presentation using the default color-coding parameters.
Graphical presentation of conserved positions in the alignment was done using Jalview [100].
Sequence presentation and shading of multiple sequence alignments was performed using the LaTEX TEXshade package [ 66].
Time zero indicates alignment to the start of stimulus presentation.
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