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A key source of evidence that present-day selection can override historically contingent effects comes from the repeated evolution of similar adaptations in different taxa.
Present-day selection appears to strongly reduce migration between habitats, however it is unclear whether the strength of this selective force was initially sufficient to drive divergence in the absence of other isolating mechanisms, or alternatively, whether reduced rates of migration played a role in instigating divergence.
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An important handicap in present-day patient selection is the inaccuracy of clinical staging.
If present-day sexual selection is stronger in dichromatic birds, our results suggest that its impact on sex-linked genomic variation is offset by other processes that lead to proportionately lower Z-linked variation in monochromatic species.
Conversely, it is possible that present-day sexual selection -- as measured by the variance in male reproductive success -- is stronger in the set of monochromatic taxa we have examined, potentially reflecting the importance of song, behavior and other non-plumage associated traits as targets of sexual selection.
Particularly in the CWS, individual cloning success via root suckering was observed to exist at distinctly higher degrees compared to our investigations in a present-day HFS (group selection shelterwood system) which is believed to represent (near-) natural forest reproduction patterns.
A simple interpretation of this pattern is that the present-day intensity of sexual selection is lower in the dichromatic species we have studied relative to monochromatic species.
Here we have suggested that RCIs are not likely targets of strong positive (or balancing) selection in present-day populations of An. gambiae.
A Discussion of Present-Day Criticism of the Darwinian Selection Theories, Together with a Brief Account of the Principal Other Proposed Auxiliary and Alternative Theories of Species-Forming" Henry Holt and Company, New York.
Other possible explanations are that this set includes genes that have recently become pseudogenes, or that balancing selection in present-day populations is maintaining high non-synonymous polymorphism levels.
This evolutionary approach can be used to test directly the influence of selection on genome structure, that is, whether present-day genome structure has been influenced by directional selection for clustering of functionally related genes.
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