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Here we present the structures of three thiophene-based non-nucleoside inhibitors (NNIs) bound non-covalently to NS5B.
We present the structures of Escherichia coli ClpP to 1.9 Å and an inactive variant that provide some clues for how this might be achieved.
Here we present the structures of both Escherichia coli YidC and Saccharomyces cerevisiae Oxa1 bound to E. coli ribosome nascent chain complexes determined by cryo-electron microscopy.
We here present the structures of human MTH1 (1.9 Å) and its complex with the product 8-oxo-dGMP (1.8 Å).
We present the structures of p300 in complex with an acetyl-CoA substrate, a CoA product, and an acetonyl-CoA inhibitor.
Here, we present the structures of both apo- and cofactor-bound forms of an euryarchaeal USP AF0826 from A. fulgidus and a bacterial USP NE1028 from N. europaea.
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The first act is called 'The Ancient Egyptians Present the Structure of the Atom,' and is from the 'Egyptian Book of the Dead,' which says that when you die you become one with the sun and are reborn every day.
Here we present the structure of meta-learning.
Here we present the structure of the DBL6ɛ domain from VAR2CSA.
We discuss our cooperative game model and present the structure of the Nash Bargaining Solution.
We present the structure of bovine C3 determined at 3 Å resolution.
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