Sentence examples for present significant disadvantages from inspiring English sources

However, these techniques all present significant disadvantages, particularly in the management of active patients.

However, as all these techniques present significant disadvantages, particularly in young and active patients, a custom-made lateral hemiarthroplasty was designed and implanted as an alternative treatment.

Despite inducing nociceptive responses, current models used to mimic OA pain present significant disadvantages, mainly in what concerns the mechanisms of OA onset and development [ 14].

However, while HGF displays good pharmacokinetic properties and high selectivity to c-MET, it also presents significant disadvantages.

While the former is unable to model the realistic soil-pipeline interaction for large scale deformations and to capture the pipeline local instabilities, the latter presents significant disadvantages in terms of elevated computational demands and required engineering expertise.

The electroporation technique presents at least four peculiarities that can represent significant disadvantages when it is compared to stable transgenesis.

Yet this approach has significant disadvantages.

And they hold at least two significant disadvantages for Bristol and Sanofi.

This support helped Mr. Thompson overcome some significant disadvantages.

But to me it has two significant disadvantages.

The uranium that makes conventional nuclear power possible has a number of significant disadvantages.