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These findings underscore our present lack of knowledge regarding peroxisome biology, which is essential for better understanding the disease progression of PBDs.
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Given the present lack of research, knowledge and training in ageing and autism, I'm not optimistic that any of this will have happened by then.
However, at present, lack of physician knowledge about DCD is a major barrier to effective management of this chronic condition.
The challenges faced for developing such methods are our present lack of in depth knowledge on the precise molecular architecture of BBB TJs as well as our incomplete understanding of the function and regulation of expression of the individual TJ components in BBB TJs.
Without any doubt, the power of the state apparatus over the production and distribution of knowledge explains the present lack of competitiveness of the French industry and the relative weakness of its small and medium size companies, which do not have the same level of recognition and support than the firms associated to national networks of power.
At present, the lack of knowledge about bona fide miRNA target genes hampers a full understanding on the biological functions deregulated by aberrant miRNA expression.
There is at present a lack of knowledge of time trends in health related quality of life (HRQL) in common patients with coronary artery disease (CAD) treated in ordinary care.
The present study revealed lack of knowledge related to preventive measures for POAG, suggesting the need for a health awareness program focused on reducing the prevalence of glaucoma blindness.
In the first of the stories, the nurse associates it with the changes detected in the patient's vital signs when there is an emotional event (like when a sedated pregnant patient hears the baby, or when a relative is present) and the lack of knowledge we still have of sensory perception in sedated patients: "…We had a 21-year-old girl with an aneurysm… I spoke to her a lot, I don't know.
Even though previous studies has been highlighting the importance of post translational modifications of CYLD such as phosphorylation [11], [12] and ubiquitination [13] for its tumor suppressor function, at the present there is a lack of knowledge of how CYLD transcription is regulated and by which signaling pathway this regulation occurs in non-transformed primary cells.
At present, there is still lack of knowledge regarding to these questions.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com