The creation of specifically matched ligand receptor pairs that are orthogonal to naturally present interacting pairs is essential for the development of small molecule-regulated gene expression systems for biotechnological applications.
After examining the different co-evolution groups we found that groups G9, G10, G12, G15 and G16 (Table 1) presented pairs of amino acids with strong evidence for their compensatory effects--that is to say they fall within 4 Å of each other in the protein structure and are therefore likely to present interacting effects.
Liszt, Mr. Lortie revealed, wasn't merely composing picture postcards; the "Années" are profound explorations of memory, the way past and present interact to create art.
At the Orange County Museum of Art in California, R. Luke Dubois' exhibit, simply entitled "Now," features digital portraits in which both the past and the present interact.
Irrespective of this, E. coli O157 when present interacted with the cells as described previously [ 33, 34].
In a beautiful structure of the extracellular portion of LDLR at low pH, it was shown that the single YWTD domain present interacted with CR modules 4 and 5 of the lipoprotein-binding region [ 33].
If the interaction is present, the interacting factors must be considered jointly.
For instance, in the pizza restaurant Chuck and Janet are "present" and interacting at the dinner table, while their grandkids are "present" and interacting in a completely different, entirely digital universe.
Contact friction is present on interacting surfaces of steel thin-walled structural members under axial folding during vehicle crash, and often occurs under relatively high contact pressure (∼100 MPa) and sliding velocity (∼6 m/s).
'Non self-management' tended to occur in contexts where people's material, intellectual or emotional resources were stretched, including poverty, low health literacy, a demanding family or social context, or multiple co-morbidity - and especially when all these factors were present and interacting.
For us, contextualising the learning means adding value to the materials and activities presented online; interacting with the learners through the instructions and guidelines; and being present in that space with them, similar to that described by Laurillard (2012).
