The state of computer hardware at the time of this writing makes the multi-locus methods presented here impractical for exhaustive evaluations of data sets with millions of SNPs and tens of thousands of expression traits.
These algorithms typically assume that a large number of anchor points are present, which is impractical in many cases.
The results suggested that an optimum level of TEVp expression leading to sufficient inducible activity (with minimal background activity) exists but the variability in expression levels between cells makes the present system rather impractical for single cell experiments.
While the methods presented here are impractical for routine intraoperative assessment, the primary aim of this study was to utilize the 3D retrospective analysis to quantify the tibial resection parameters used in varus knees treated with KA TKA.
Because it is impractical to present a state transition diagram for a CRN with an arbitrary number of channels, we present an illustrative example in Fig. 2 which shows the allowable state transitions from and to state (1,1) in a Markov chain with three channels.
They are impractical at present for industrial field application in which we have to calibrate a myriad of other discrete and continuous parameters, including fluid contacts, rock compressibility, and relative permeability.
Nevertheless, at present, it is still impractical to use information from genes that are identified by general identifiers only.
At present, it is still impractical to screen all possible drug combinations for different diseases.
This factor, in addition to the modest antinoceptive effects evident in the present study, made it impractical to detect sex differences with the selective KOP receptor agonist.
However, given a large number of potential underlying factors and our current incomplete understanding of their interactions, untangling and explicitly accounting for each of them individually would be impractical at present [ 20, 30].
