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Other models that have been used in the papers we reviewed appear too complicated for randomised trial data of usually fairly small sample size, have only been shown to be of (sometimes rather slight) benefit in particular data sets, and present formidable problems of implementation to applied analysts.
The combination of high spinal cord injury and neurovesical dysfunction can present formidable problems in urological management.
Lateritic residuum remains an excellent sample medium if present, again with widespread haloes, but where it is absent, leaching and the restricted haloes in upper saprolite present formidable problems.
During this time, we've been deeply engaged economically, politically and militarily with countries that, individually, present formidable problems.
Kinematic analysis of foetuses' spontaneous and unskilled upper limb movements presents formidable problems.
The treatment of challenging fractures and large osseous defects presents a formidable problem for orthopaedic surgeons.
The Book of Mormon poses formidable problems for scholars.
Abbott Laboratories told the Ninth Circuit that allowing challenges based on sexual orientation "would present formidable practical problems".
In India, tube wells accounted for nearly one-half of the net irrigated area by the late 1980s .48Because it deals with the complex interaction between society and the physical environment, aquifer management presents a formidable problem of policy design.
Factors affecting HIV-1 latency present formidable obstacles for therapeutic intervention.
The issues of non-selectivity and congested IP space, however, present formidable challenges for the successful clinical development of these compounds.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com