We have at present duplicated his result in identifying the Mendeleev Number as the single best feature, and we have produced a new result for the case of two features: namely, we have identified the Mendeleev number with the valence electron number as the best combination of two features.
The major exclusion criteria were as follows: (1) studies that presented duplicate data, (2) studies that included only cancer patients (i.e., no healthy controls), and (3) studies that investigated benign diseases compared with controls.
Of the 144 papers where full-text articles were reviewed, we excluded a total of 28 articles; 24 studies did not meet eligibility criteria, and 4 presented duplicate data.
For example, to remove the 'template switching' effect [ 41], all the SE candidates that presented duplicated sequences of more than 6 nucleotides at both sides of the junction were discarded as likely reverse transcription artifacts during the process of library preparation.
It has been reported that at least 20 percentof zebrafish genes are present in duplicate [27], and it is possible that a fraction of the duplicate copies might have been lost, or that some missing duplicates may be present in the genome but not yet discovered.
To test our ability to analyze human plasma, we received 30 blinded samples, each of which was present in duplicate or triplicate (as a further blind, the laboratory was told that only duplicates were present).
Each case was present in duplicate on in this array.
Indeed, when the putative zebrafish orthologs of 74 human genes on chromosome 17 were examined, only 15 (20%) were present as duplicate genes [25], [26].
When the putative zebrafish orthologs of 74 human genes on chromosome 17 were examined, Postlethwait et al. found that 15 (20%) are present as duplicate genes [25].
