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We are in a realm here where, usually unbeknown to them, characters are living in a present defined by a fictional history.
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A consistent foliation is present, defined by the alignment of muscovite- and quartz-rich layers of contrasting colours.
Second, a PRN regimen is established on demand, and intravitreal injections are given if CNV activity is present, defined by fluorescein leakage at FA and/or the presence of abnormal intraretinal or subretinal fluid assessed by OCT, until cessation of activity.
This disposition, however, will never be respected by farmers in the present context defined by a shortage of land.
Cretaceous normal faulting, without major amounts of denudation, led to the development of the present east coast topography defined by a tectonically juvenile escarpment.
By 'parental' and 'offspring' network we mean the original and the copied networks present in adjacent layers defined by a topographic map.
In the development of targeted therapies with prior evidence that the treatment effect may be stronger (or only present) in a subgroup defined by a biomarker, one faces several design options when planning a clinical trial.
For the analysis of the data presented here, gene sets defined by a common annotation were considered based on the Gene Ontology categories for 'cellular component' (GOTERM_CC), 'molecular function' (GOTERM_MF) and 'biological process' (GOTERM_BP).
Patients with cancer were excluded from our study if they presented with an aplasia (defined by a polymorphonuclear neutrophil count of less than 0.5 G/L) or were treated with a high dose of corticoids (estimated as treatment superior to 10 mg equivalent prednisolone/day or more than 700 mg equivalent prednisolone accrued the first day of inclusion) or both.
Half of the probe sets of (767/1552 = 49.4%) were detectable (defined by a present call) in all tissues we tested so far, albeit in most cases at varying levels.
In particular, we examined if patients presented with chronic kidney disease (defined by a creatinine clearance <60 ml/min), and had more than one cardiovascular underlying disease (myocardial infarction, stroke, lower limb arteritis).
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