The present data imply that avian IL-15 has, at least partially, a different function compared to its mammalian counterpart, and in addition, chicken innate immune responses might be affected differently by n−3 PUFA compared to mammals.
Although there is evidence that, in septic patients, a clear dissociation between ACTH and cortisol levels exists [38], our present data imply that, in rodents, the physiologic feed-back loops of the HPA-axis may be intact during the early course of experimental sepsis (Figures 1A, B).
The present data imply increased inhibition resulting in a lack of facilitation following painful CS.
The present data imply that the level of virus titers in the initial target organ, e.g., the liver, at 2 to 3 days p.i. may determine the severity and ultimate outcome of RVFV infection in mice.
The present data imply that C. jejuni colonization of the B line induces a localized suppression of both the innate (epithelial cell regulation, inflammation) and the adaptive responses that allows the bacteria to colonize the ceca.
The present data imply reduced IRS-1 signalling in South Asians, which may manifest as impaired insulin-stimulated glucose transport and a degree of insulin resistance in the muscle, although this did not correlate significantly with our whole-body measurement of insulin sensitivity.
These present data imply that disturbances of hyaluronan metabolism may be associated with vascular damage in type 1 diabetes patients.
The present data imply that the impact of the TIP peptide on the lung water content may be short-termed but traceable even under sub-standard ventilation.
Similarly, the present data imply an addiction of HCC cell lines to DNA-PKcs for their proliferation and survival, especially when subjected to DNA-damaging insults.
