We demonstrated significant functional divergence was present at the protein sequence level between each FFRP.
The single fixed difference in HBD between humans and great apes replaces two functionally equivalent amino acids, a valine by methionine (V127M) and it is already present at the Denisova sequence (Reich et al. 2011; Meyer et al. 2012).
In some strains, although the SINE was present at the locus, the sequence showed some truncations or short deletions.
At present, the sequence information of CXCL10 gene for human [ 13], mouse [ 14], cattle [ 15], sheep [ 16], goat [ 17], and pig [ 18] had been reported.
A study similar to that presented here, looking at the sequence diversity among GII-4 noroviruses and in silico analysis of the changes observed, was published recently by Siebenga et al [9], however the interpretation of the data by Siebenga et al is not in agreement with the data presented here.
They found that 99.95 % of all taxa present in the six-year survey were also present at the single deeply sequenced time-point, and that the sum total of species richness found in the 72 monthly observations comprised less than five percent of the total diversity in the deeply sequenced time point.
Putative SNPs include all base variations involved in the sequence assemblies with at least four sequences present at the SNP position with minor allele sequences represented at least twice.
Sequences from Danaus plexippus plexippus (Pfamseq_acc: Q6J977), Tirumala hamata (Q6J937) and Agathis sp. DMA-1998 (Q9T6C7) were excluded because of the large number of ambiguous residues present at the 5' end of the sequences.
The results, hyperlinked in the column named "Mean average length of sequence with gaps and link to truncation analysis" shows a representation of the alignment, as a.txt file, that indicates the deletions present at the extremes of the sequences within a given cluster.
When regions proximal to the 5' end of the query genes were conserved, the sequence was extended up to the proximal Start codon (ATG) in the approximately expected position, when present; otherwise, the sequence was initiated at the first conserved region.
