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However, our data also suggest that additional G-quadruplex structures are present and resolved independently of FANCJ (Fig 7D).
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However, the clinical presentation and evolution of kidney function did not suggest, in any of patients, that interstitial nephritis could have been present earlier and resolved before the biopsy.
However, these are limited to structures presented by and resolved for natural proteins.
After optimisation of GC-MS parameters, the obtained chromatograms presented separated and resolved peaks, which permitted the identification and quantification of the target compounds.
Previous infection was present in one case and resolved after debridement.
There were no diagnoses of deep venous thrombosis but superficial pin tract infections were present in 5 cases and resolved in 4 using local antiseptic and an oral antibiotic regimen.
Choroidal involvement was present in 15 patients and resolved in ten (clearance of inflammatory activity on funduscopy) whereas five had a partial response.
Papillitis (the presence of inflammatory disc swelling) was present in eight patients and resolved in seven patients (no staining on FA), one had partial response (less staining on FA).
Third, the present study also explicitly stated and resolved the sign correction issue of latent components in PLS, which has been neither stated nor resolved in a previous study that used PLS as a pathway-level aggregation method [ 4].
In previous work [20], [21], [48], we presented implementations of multicompartment systems and resolved the problem of readjusting vesicle formation/composition as well as of losing specificity by using linkers consisting of biotinylated DNA single strands (biotin-ssDNA) that were anchored by long and flexible phospholipid-grafted biotinylated PEG tethers via streptavidin as a connector.
In previous studies, we presented implementations of multicompartment systems and resolved the readjustment of the vesicle formation procedure as well as the loss of specificity by using linkers consisting of biotinylated DNA single strands that were anchored to phospholipid-grafted biotinylated PEG tethers via streptavidin as a connector.
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