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Up until the present, additive manufacturing has been limited by the technology's limitations, largely in terms of the size of products created.
Figure 1f represents the case of an interaction when no main effect is present (additive by additive epistasis) and is included here due to it's special status as being often considered as the most diabolical form of statistical interaction.
Pioglitazone and candesartan in combination were demonstrated to present additive protective effects on renal fibrosis in an experimental mouse model, suggesting that their use in combination would be an effective treatment for chronic kidney disease [ 19].
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We show that blocking Pim kinase activity strongly suppressed the growth of myeloma cells and that proteasome and Pim kinase inhibitors presented additive inhibitory effects in these cells.
These results were analysed using the Chou and Talalay method [ 24] showing that AZD 1208 and bortezomib presented additive effects to inhibit myeloma cell growth.
To determine whether drugs presented additive or synergistic activities, the Chou and Talalay method was used through the Compusyn software (http://www.combosyn.com) [ 24].
We present an additive manufacturing of thin-walled Fe-Al samples using the Laser Engineered Net Shaping (LENS) technique.
Here, we present dropwise additive manufacturing of pharmaceutical products (DAMPP) as an alternative to conventional pharmaceutical manufacturing methods.
If no interaction effect was present, an additive model (without interaction) effect was analyzed.
We first describe the NMM criterion, and then present the additive optimization method.
Further, we have implicitly assumed that the only bias present is additive (the present analysis does not consider multiplicative bias), and this should not impact the regression slope.
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