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The credit card sale is not large enough to present a significant obstacle to the First Union-Wachovia merger.
The number of outbreaks, particularly the ongoing outbreak in Nigeria (96), indicates that cVDPVs present a significant obstacle to the eradication of virulent polioviruses.
With close monitoring of the patient, suitable medication and rehydration, most cases of diarrhoea can be managed effectively and do not present a significant obstacle to the clinical use of ILF.
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The redundancy among ontology terms presents a significant obstacle in result interpretation.
Private sector data collection presents a significant obstacle to democracy that we have yet to reckon with.
It decrees that racism no longer presents a significant obstacle either to individual success or to collective self-realisation.
The limited braking area at Loring, however, presents a significant obstacle.
(Such constant change makes it hard to develop antiviral drugs that will remain effective for long, and it has also presented a significant obstacle to the development of an AIDS vaccine).
The Second Circuit's decision makes for a more predictable legal environment for foreign central banks that choose to maintain reserves in New York and presents a significant obstacle to creditors of a country who look to central bank assets in the United States to collect on unpaid judgments.
This presented a significant obstacle.
Unfortunately the lack of tools to selectively perturb these subcellular domains has presented a significant obstacle to understanding the potential biological role of localized cAMP signaling events.
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