Sentence examples for present a major issue from inspiring English sources

Until the Brock story broke, few people in the political world had believed that these objectives would present a major issue.

Due to the retrospective nature of meta-analysis studies, there is no control over the initial study design of each cohort, and confounding variables present a major issue.

Still, this may not present a major issue in our case because we are using an oncolytic strategy in which the therapeutic transgene, itself, is the Ad5 E1 gene.

At present, a major issue is to build up expertise within the clinical community to run trials in nutrition-related matters to obtain evidence that can support decisions on interventions and that provide good value for money.

Access to raw materials would therefore have presented a major issue for ancient potters, especially because significant quantities would have been needed to support large scale production.

Ajay K Kakkar: Dosing presents a major issue with some LMWHs.

European Regulators share the industry view that the high compound attrition rate presents a major issue and have called for innovative (improved) methods in drug development and evaluation, and more frequent and early dialogue with industry.

Possible adverse health effects due to electromagnetic fields (EMFs) from cellular phones and base stations present a major public health issue across Europe.

Interestingly, CRP does not present a major noise-to-signal ratio issue [ 10].

Increased process variability and reliability issues present a major challenge for future SRAM trends.

The response by the industry is that, while it admits there are incidents involving contaminated air, there is no evidence it presents a major safety issue or health hazard, and the amount of TCP those on an aircraft might ingest is too small to present 'a significant health risk'.