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Additionally, eventual adverse events caused by high doses and general nervousness surrounding a first-in-human drug administration can affect the autonomic responses altering the QT/RR relationship which can also present a limitation for the use of Phase I data in simulation studies to detect clinical relevant QTc prolongation.
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At temperatures around 70 K, correlation lengths are on the order of 10 nm, presenting a limitation for device operation.
The increase in viscosity, adsorption of polymers onto the reservoir rock presents a limitation for the use of polymers.
This is a choice made to ensure specificity, and does not present a limitation when searching for TEI affecting phenotype as the impact of a nested TE insertion is likely minor compared to that of the already present TE.
Information on birth weight and distance to facility and nutritional status, known risk factors of under-five mortality, were not collected at the RDSS and hence were not available for analysis, presenting a limitation of this study.
The increasing volume of scientific data and the limited scalability and performance of storage systems are currently presenting a significant limitation for the productivity of the scientific workflows running on both high-performance computing (HPC) and cloud platforms.
Propagation of elite varieties has been achieved through somatic embryogenesis (SE) but low efficiencies and genotype dependence still presents a significant limitation for its propagation at commercial scales.
However, pre-existing antibodies present a significant limitation to achieving optimal efficacy for the AAV gene delivery system.
The present proposal still considers a limitation for the ZIP coefficients, in order to identify the power ratio in terms of constant impedance, constant current and constant power.
To overcome these limitations, we present a Toolbox for Integrating Genome-scale metabolism, Expression, and Regulation (TIGER).
To counter these limitations, we present a new methodology for multi-plant HENs synthesis directly using process streams.
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