The award of a prize to Karman, who stands for freedom of speech and opposition to President Saleh's government, presents a difficulty to the Yemeni government and its Western supporters.
From a clinical point of view, this means that most manual activities present a difficulty that varies according to the underlying diagnosis and that various pathologies may affect differently the achievement of daily activities.
For the Ile-de-France, the limited number of regional hospitals does not appear to present a difficulty for evaluating performance.
Weak associations and small effects, assuming they are plausible and supported by laboratory studies, present a particular difficulty to classical inference methods.
Individual researchers have developed their own techniques for designing and testing these neural networks, and this presents a difficulty when trying to learn lessons and compare results.
Issues of inclusion and exclusion were also raised by Beth who suggested that the intention not to refer explicitly to infants and toddlers presented a difficulty in her work which needs to be rectified: They should be included, considering I predominantly work with zero to two's and they fit under the term infant, babies and toddlers.
Post-Doncaster defeats for Nijinsky, notably in the Prix de l'Arc de Triomphe, presented a difficulty for the race in trying to attract the very best performers.
Time-consuming therapies, such as physiotherapy for juvenile arthritis or cystic fibrosis, presented a difficulty as this was time spent to the exclusion of other family members and other activities; some caregivers felt that the regimen had to be contained so that it did not impinge on 'normal' activities [ 26].
In event detection, data collection presents a difficulty.
In our present study, there was a difficulty to detecting murine cytotoxic T cells, because the recognition of antigens by CTLs in a mouse model is restricted by self class I/II MHC alleles.
