Sentence examples similar to present a considerable hurdle from inspiring English sources

Existing cell culture methods fail to expand the airway epithelial progenitor pool, presenting a considerable hurdle for progression to clinical trials.

Cutaneous diseases, specifically ones with significant genetic components are ideal candidates for topical siRNA based therapy but the anatomical structure of skin presents a considerable hurdle.

The structural similarities in active site architecture across human CA isozymes are substantial and for drug discovery that is dependent on selectively targeting specific CA isozymes this presents a considerable hurdle [ 3].

Thyroid nodules present a considerable diagnostic challenge.

Many of those interviewed expressed that the Japanese "shyness" was a considerable hurdle.

That's a "considerable" hurdle, Dueber says, but likely doable within a few years.

Nowadays, insurgence of resistance against chloroquine is a considerable hurdle for malaria control [1].

This signaling cascade therefore has received considerable attention in drug targeting, but balancing efficacy with safety (i.e., the therapeutic index) has proved to be a considerable hurdle to overcome [ 2].

After all, even with all sail doused, the mast presents a considerable amount of windage aloft.

Yet it presents a considerable one, she says.

"Relegation presented a considerable challenge for us financially.