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MeDIP was selected because the methodology supports high-resolution and high-throughput DNA methylation profiling, is sensitive to the overall number of methylated cytosine residues in the regions of interest, and its sensitivity is independent of the presence of recognition sites for methylation-sensitive restrictases [97], [98].
Detection of a particular transcript by cDNA-AFLP depends on the presence of recognition sites for restriction endonucleases in the complementary DNA sequence.
We searched for miRNA recognition motifs in the linc-MD1 sequence and found that the presence of recognition sites for miR-133 and miR-135 could be reliably predicted.
As indicated in "Methods" each nucleotide sequence from more than 1,190,000 annotated Alu repeats sequences has been searched for a presence of recognition sequence of restriction enzymes, a number and positions of these sites in Alu repeat sequences have been determined.
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All the molecules have been designed on the basis of the presence of specific recognition patterns consisting of hydrogen bond acceptors (or electron donors), carbonyl, chloro groups with precise spatial separation and structural features (lipophilicity, positive charge at neutral pH and presence of aromatic rings).
The model also accounted for the presence of a recognition nucleation over a few bases followed by the rapid extension of the synaptic complex, in agreement with previous theoretical studies [26].
Although there is no detailed experimental picture of the association between OmpA-like proteins and PG mesh, previous crystallographic and NMR studies on the proteins of this family established the presence of separate recognition sites for glycan and peptide moieties of PG [6], [8], [9].
The presence of XbaI recognition sites for PFGE and the variability of tandem repeated motifs in MLVA.
This spliceosomal complex assembly requires the presence of conserved recognition sequences in the pre-mRNA for silencers, enhancers etc.
SR proteins are characterized by the presence of RNA recognition motifs (RRM) in the N terminus and the presence of RS domain in the C terminus.
However, generation of tags via deepSuperSAGE depends on the presence of a recognition site for the anchoring enzyme, while MACE generates a tag out of every transcript.
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