In order to improve the specificity of the assay – a specificity that is negatively affected by the high sensitivity of the RT PCR technique – establishing a cutoff was pursued instead of performing a negative immunological preselection or another method to eliminate fractions of nonepithelial blood cells that might express CK-19 at low levels.
A method using preselection of the most similar voxels, multithreading, and blockwise implementation is presented in [7].
Meanwhile, in order to avoid too low D2D link throughput, which might become the throughput bottleneck of the entire transmission path, an estimation method of relay preselection is proposed in this paper to reduce the possibility of abandoning the preselected relays in the phase of relay verification.
Secondly, we include commonly used measurement variables on ECGs without preselection and use dimension reduction methods to identify biomarkers.
We also performed a pathway analysis with GSEA (Broad Institute), a method that does not require preselection of genes by a statistical threshold but uses the whole dataset.
Phylogenetic reconstructions were performed using clustering neighbor-joining method (MEGA 5.1) with the preselection of an adequate model of nucleotide substitutions.
The goal of this chapter was to provide tools for using an alternative preselection approach, called, for example, design-by-analogy method or something like that.
Because the number of candidate isoforms grows exponentially with the number of exons, the above methods are either computationally expensive for genes with many exons (such as NSMAP or SLIDE) or include a preselection step to reduce the number of candidates, which may alter the method accuracy.
However, even though the sure independence screening seems to be a decent method indeed, and we have contented ourselves with using it for the marker preselection for the time being, there probably is room for improvement in this respect.
15 Owing to the complexity of the clinical images, a non-medical individual performed the preselection of an area of interest prior to the automated segmentation phase of all methods.
