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The proportion of patients with prescriptions of both agents increased from 0.34%% before the index date to 2.2 % after the index date.
For every million prescriptions of both rofecoxib and celecoxib, we found a 0.5 percent increase in MI (95 percent confidence interval, 0.1 to 0.9), explaining approximately 50.3 percent of the deviance in yearly variation of MI-related hospitalizations.
For the medication-based criterion, prescriptions of both a β-agonist and an inhaled glucocorticoid were required.
Non-use of drug was defined as less than two prescriptions for either drug; mixed use (⩾2 prescriptions of both PPI and H2RA) was not evaluated.
Asthma in offspring was defined as at least two prescriptions of both a β-agonist and an inhaled glucocorticoid and/or a hospital diagnosis of asthma during follow-up.
The 110,102 linked patients filled 4,816,247 prescriptions of both GPs and medical specialists during the period 1999 2003, with an average of 43.7 (SD = 68.6) prescriptions per patient.
Similar(53)
Because non-malarial causes of febrile illness will be identified, implementation should also include training on rational prescription of both antimalarials and antibiotics.
This suggests that the prescription of both celecoxib and rofecoxib may have 'leaked' to population groups who would not previously have received an older NSAID.
All residents in the intervention group received at least one step change increase in dose or prescription of both ACEi and β-blocker.
Taking into account a quarterly documentation of prescribed drugs, a separate prescription of both a LABA and an ICS compound was considered as concomitant usage of LABA and ICS if given in one quarter (irrespective of any other drugs).
Our results are not likely to derive from an overlap between the use of diuretics and RAS antagonists, since concomitant prescription of both classes was observed in only 28.8% (n=31) of all cases.
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CEO of Professional Science Editing for Scientists @ prosciediting.com