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Producers offer retailers financial inducements to substitute their own products for those that may have been prescribed by a doctor or other prescriber: practices like this are well known and further undermine trust in other parts of the system [ 23, 25, 28].
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In addition to reporting, 12 (60%) hospitals changed prescribing of vancomycin (i.e., prescriber practice change).
Eight (40%) hospitals reported at least one prescriber practice change (many hospitals combined several hospitalwide change in prescriber practice) that was applied hospitalwide; these changes encompassed 22 ICUs (Table).
In addition, the retrospective nature of ascertaining the description of changes in prescriber practice may involve some recall bias.
In addition, hospitals began activities to reduce vancomycin use through changes in prescriber practice independent of the investigation.
The reasons unit-specific change in prescriber practice in ICUs were associated with decreases in vancomycin use and VRE are not certain.
This article sets to analyse whether early prescribers of newly marketed drugs are consistently associated with potential prescriber, practice, and patient characteristics—as well as with new drug attributes.
After data were adjusted for changes in prevalence of methicillin-resistant Staphylococcus aureus, changes in specific prescriber practice at ICUs were associated with significant decreases in vancomycin use (mean decrease -48 defined daily doses per 1,000 patient days, p<0.001).
Suggestions on how to optimize clozapine utilization have been published but more efforts are needed to properly inform and support prescribers' practices.
Prescriber beliefs at a population level did not necessarily translate to prescribing practices at an individual level.
There is some evidence available on the prescribing practices of district nurses and health visitors and early independent extended prescribers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com