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Precise definition and validation of clinical phenotypes are key prerequisites to identify the genetic basis of complex diseases, since a principal goal of genetic research is to identify specific genotypes that link to specific phenotypes (30, 31).
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Disentangling the role of epidemiological factors in plant pathogen emergences is a prerequisite to identify the most likely future invaders.
A sound habitat classification, leading to spatially explicit accounts on the distribution of marine habitats and communities, is a prerequisite to identify conservation priorities, based on appropriate methods for assessing habitat sensitivity to human disturbance, aimed at preventing habitat loss.
A small sample size also makes it difficult to identify CNAs that co-exist or are mutually exclusive, which is a prerequisite to identify any common pathways that may be deregulated in EOC through alterations in gene copy number.
The only prerequisite to identify candidate genes is that the genes of interest are expressed in the sample tissues.
A prerequisite to identify novel therapeutic targets for human tumors is a good understanding of the pathogenetic mechanisms.
This is in part due to the still limited knowledge of the molecular regulation of lymphatic development, a prerequisite to identify pro- or anti-lymphangiogenic candidates.
Furthermore, the participants were not asked to identify the adjacent octaves of the presented tones, as for AP it is a most notable prerequisite to identify the correct chroma.
Integration of additional information pertaining to subcellular localization and protein expression profiles becomes a prerequisite to identify feasible RBC parasite interactions, owing to the growth and development of the parasite in mature RBCs.
Accurate epidemiological data are a prerequisite to: identify people at risk in the population, assess the efficacy of preventive strategies and curative therapies at a population level, carry out work force planning.
No independent markers are yet available to predict the behaviour of any individual prostate cancer, particularly its potential to metastasize, and there is now an urgent prerequisite to identify and characterize genes specifically involved in determining the metastatic phenotype of prostate cancer cells before any biologically appropriate treatment modality can be devised.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com