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The first factor is prior knowledge, or the prerequisite understanding necessary for students to solve a problem.
Therefore, the characterization of ADAR expression and identification of alternative ADAR variants is an important prerequisite for understanding the mechanisms for regulation of RNA editing and the causes for deregulation in disease.
The structure of human AQP2 is a prerequisite for understanding its function and for designing specific blockers.
Understanding the relevant notions is thus a prerequisite for understanding key issues in contemporary analytic philosophy.
Understanding the interaction between two or more "hits" is a prerequisite for understanding mechanisms of permanent lung injury in preterm infants and for individualization of therapeutic interventions in order to promote recovery from the stressors.
Understanding the phylogenetic relationships within the Neodermata is an essential prerequisite for understanding the evolutionary origins of endo- and ectoparasitism as well as of the complex life cycles of flatworms.
The characterization of the biophysical mechanism by which co-operativity modulates the affinities of transcription factors for binding to CBP is a prerequisite for understanding how gene transcription is regulated.
Understanding the molecular mechanisms underlying plant defenses and fungal pathogenicity is a prerequisite for understanding the host-pathogen interaction and can contribute to the development of new strategies of crop protection against pathogen.
A prerequisite for understanding their functional relevance is knowing all their locations for a protein of interest.
Animal models that accurately recapitulate human pathology are a critical prerequisite for understanding pathogenic mechanisms and developing new diagnostics and therapeutics for TBI and CTE [ 46].
Evaluation of redox conditions in groundwater pollution plumes is often a prerequisite for understanding the behaviour of the pollutants in the plume and for selecting remediation approaches.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com