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Binding of both substrate molecules to the active site seems to be a prerequisite to trigger this transition.
Therefore, whether or not anti-TNF-α agents can bind to the transmembrane form of TNF-α is prerequisite to trigger antibody dependent cell mediated cytotoxicity (ADCC), complement dependent cytotoxicity (CDC), apoptotic and outside-to-inside signaling mechanisms.
The prerequisite to trigger the next step of the cascade is the accumulation of either OAS or OAH which are needed for CysR-mediated gene regulation.
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These data suggest a key role for FcεRI in triggering an a wide range of inflammatory responses, as the over-expression of cytokines and chemokines is a prerequisite to triggering inflammation, including vascular permeability, and leukocyte and lymphocyte recruitment, differentiation and activation.
Our data support a model in which the binding of ADF/cofilin is required to trigger a structural change of the actin filaments, as a prerequisite for their disassembly by Aip1.
That seems to trigger the desired reprogramming.
Ashley Banjo knows how to trigger audience response.
Time to Trigger.
That started to trigger our attention".
Set conditions to trigger the rule.
Tobacco use is known to trigger migraines.
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CEO of Professional Science Editing for Scientists @ prosciediting.com