This might suggests that physiological clearing of serotonin from the synaptic cleft is a prerequisite for triptan response.
It has been shown that recognition of the pathogen or its effectors increases [Ca2+]cyt elevation in plant cells, which is a prerequisite for hypersensitive response development [ 56- 58].
As migration of antigen-loaded APCs to the draining LN is a prerequisite for this response in vivo, we first analyzed the cellular composition of draining LNs in wt and myeloid pten -/- animals after induction of CIA.
Physical activity modulates expression of metabolic genes and may therefore be a prerequisite for metabolic responses to environmental stimuli.
Amino acid catabolism with generation of ammonia appears to be a necessary prerequisite for this excretory response to occur.
Thus, the ability of B-cells during chronic infection to express AID, the prerequisite for CSR, in response to different stimuli could be evaluated in vitro.
A susceptible H-2 haplotype is therefore a prerequisite for the autoimmune response.
It is clear that quantitatively defining the characteristics of an outbreak is an essential prerequisite for effective reactive response.
Initial studies indicated that inclusion of an electron donor such as acetate in the agar plate was a prerequisite for a motility response toward an electron acceptor, suggesting that active cell metabolism was required.
