Sentence examples for prerequisite for modification from inspiring English sources

This might be due to the drastic decreasing of 2MeH3K9, which is prerequisite for modification of tri-methylation on the loci.

We have previously demonstrated Siz1-dependent in vitro sumoylation of PCNA in the absence of DNA (Windecker and Ulrich, 2008), but if clamp loading were the main prerequisite for modification in vivo, association with DNA would also stimulate the reaction in vitro.

This indicates that DNA binding of Siz1 might not be a prerequisite for efficient modification of PCNA in vivo.

This is a key prerequisite for disease modification and thus holds promise for a disease-modifying effect of anle138b in PD patients.

However, this prodomain binds directly to LARGE, an event that is a prerequisite for functional modification of the mucin-like domain of α-dystroglycan (Kanagawa et al. 2004).

Precise knowledge of all the genes influencing quality and resistance traits is an absolute prerequisite for such modifications.

Although pectins are mainly present in primary cell walls [43], [44], pectin methylesterification appears to be a prerequisite for lignin modifications during secondary cell wall deposition in xylem cells [45].

Ubiquitination of this histone on residue K123 is a prerequisite for histone H3 modification and is essential for a variety of cellular processes, including gene expression and DNA repair (Dover et al. 2002; Robzyk et al. 2000).

As a prerequisite for targeted genetic modifications, the complete genome sequence of the organism has to be known.

As a prerequisite for targeted genetic modifications, the preferably complete genome sequence of the organism has to be known.

The prerequisites for dose modifications were set as follows: (i) any episode of grade 4 neutropenia of >7 days duration, (ii) any episode of febrile grade 4 neutropenia, (iii) any episode of grade 4 thrombocytopenia and (iv) any non-haematologic grade 3 or 4 toxicity excluding nausea and vomiting, musculoskeletal and arthritic pain (myalgia/arthralgia syndrome) and alopecia.