Sentence examples for prerequisite for its function from inspiring English sources

Finally, by immunoprecipitation, we showed that coxsackieviral polymerase 3D was post-translationally modified by ubiquitination and such modification might be a prerequisite for its function in transcriptional regulation of viral genome.

We also confirmed that mutations of Fkh1/2 sites in ARS607 did not abolish the recruitment of the ORC complex to the origin, indicating that Forkhead binding to ARS607 is not prerequisite for its functioning as a DNA replication origin (supplementary Fig S1 online).

The structural architecture of such a force sensor determines its response to force and must assure both activity and mechanical integrity, which are prerequisites for its function.

The six transmembrane domains are responsible for the oligomerization of LMP1, which is prerequisite for its precise function.

In this study, we demonstrated nuclear localisation of WT1 protein after transfection, indicating that one prerequisite for its suppressive function was fulfilled.

Indeed, CBP/p300-induced PLZF acetylation at its zinc finger 9 (ZF9) is a prerequisite for its repressor function [ 19] and its deacetylation is thus necessary to modulate its cellular activity [ 6].

The structure of human AQP2 is a prerequisite for understanding its function and for designing specific blockers.

Interestingly, mutation of the Cdc5 NLS (and disruption of nuclear import machinery) also altered localization of Cdc5 to the SPB and the bud neck, suggesting that nuclear translocation of Cdc5 is indispensable for its function, especially prerequisite for its proper localization to the SPB and the bud neck.

This suggests that Sli15 phosphorylation is a prerequisite for its mitotic checkpoint function and that its dephosphorylation, which normally occurs in anaphase, inactivates the checkpoint.

We demonstrated that chromatin is accessible at the risk locus, a prerequisite for its impact on astroglial function.

The TORC1-Type2A pathwaytase pathway mediates nucleocytoplasmic transport of Cdc5, which is prerequisite for its proper localization and function.