The aim of the present work was to prepare and evaluate the sustained release of potassium chloride formulations.
To overcome the above drawback, this study was carried to prepare and evaluate the pellets containing furosemide solid dispersion (SD) for oral administration prepared by extrusion/spheronization.
The objective of this study was to prepare and evaluate the radioprotective efficacy of orally active amifostine enteric microcapsules (amifostine mc).
We have prepared and evaluated the performance of natural graphite (NG)/agglomerated carbon nanotubes (ACNTs) composite materials for future mechanical dampening devices.
To solve those problems, a thermosensitive in situ gelling and mucoadhesive ophthalmic drug delivery system was prepared and evaluated, the system was composed of poloxamer analogs and polycarbophil (PCP) and betaxolol hydrochloride (BH) was selected as model drug.
In this work, we prepared and evaluated the aptamer-labeled paclitaxel-loaded poly(lactic-co-glycolic acid) (PLGA) nanoparticles (Apt-PTX-PLGA NPs) which can ameliorate drug bioavailability and enable accurate drug targeting to cancer cells with controlled drug release for cancer therapy.
Hence three isomeric monofluorophenyl analogues were prepared and evaluated; the 2- and 4-isomers (16 and 18, respectively— Table 2) were slightly more potent than the 3-isomer 17, with all showing very similar levels of in vitro activity against the parasite.
In order to determine the DL and QL values, samples of the pheromone rhynchophorol were prepared and evaluated with the aid of the signal-to-noise ratio tool, provided in the TurboMass software program (version 5.4.2.1617), installed in the equipment used.
A series of aza inhibitors (4 9) of chorismate mutase (E.C. 5.4.99.5) was designed, prepared, and evaluated against the enzyme by monitoring the direct inhibition of the chorismate, 1, to prephenate, 2, conversion.
Molecularly imprinted polymers (MIPs) are prepared and evaluated for the effective removal of the genotoxic impurity (GTI), 4-dimethylaminopiridine (DMAP), from a Mometasone furoate (Meta) solution, used as a case study relevant for the pharmaceutical industry.
