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Having a look at the docking rank and score of the respective bioactive between the two preparations, we found that the maximum difference of the rank is attributable to a bioactive ligand that showed a difference in its protonation state between the two preparations.
For the nine human islet preparations we found that four of the genes demonstrated significant down-regulation upon cytokine-stimulation.
From several nerve-muscle co-culture preparations we found phospho-cortactin at >80% of nerve-induced AChR clusters (Table S1).
However, in separate current-clamp studies using the same cell preparations, we found that ∼70% (11 of 16) of cells exhibited a "working", ventricular-like AP phenotype, with the balance showing nodal-like APs (data not shown).
Moreover, in isometrically twitching preparations we found a frequency-dependent increase in diastolic tension compared to WT specimen which may be an additional indication for increased diastolic Ca2+.
In fixed preparations, we found that the majority of embryos expressing GFP-Sak (60%–80%, depending on the line) arrested early in development with mitotic defects (not shown).
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In addition to mental preparation, we found that patients who prepared physically felt that being in better shape before surgery would give them a better surgical outcome.
In a previous study (Rumpf et al., in preparation), we found that anodal transcranial direct current stimulation (tDCS) applied to the primary motor cortex (M1) immediately after a training session enhances consolidation of motor sequence learning in healthy older adults.
Using a stimulation paradigm in which associative long-term facilitation (LTF) occurs at one input and non-associative LTF at another input to the same postsynaptic neuron in an Aplysia sensorimotor preparation, we found that each form of LTF is reversed by inhibiting distinct isoforms of protein kinase M (PKM), putative PRPs, in the postsynaptic neuron.
In Alcian blue preparation we found that the cartilaginous skeleton was almost absent.
Using this preparation, we found that B. anthracis PGN stimulated TNFα production from whole blood, and that the monocytes were the sole responding population.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com