For this reason, and in consideration of the wide variety of possible application in the field of radiopharmaceutical preparations, validation of analytical methods will be the subject of a dedicated document.
J.L. performed the antibody array characterization, the RNA preparation, and validation and western blots, including those on histone modifications conducted also by A.S. R.F. was responsible for mouse genotyping, sectioning, and quantification of immunohistochemistry. J.B. conducted all the experiments related to in vitro characterization of the histone modifications using purified proteins.
In addition, the results on 5% training data, is likely to be more useful in real-time systems as in real applications the size of the test data keeps on growing at a rate higher than the training data, mainly because of the labor intensive processes involved in the preparation and validation of the training data.
One possible explanation for this discrepancy is the variability in hMSC preparation and validation.
CL, ZW, XS, QZ, DZ, ZS, FL and CH participated in sample preparation, data validation and study coordination.
Preparation and validation of the human chromosome 1 genomic-clone microarray was previously described [ 55, 70].
CC carried out the follow-up of patients, obtained authorization from ethics committee, and participated in data collection, preparation and validation.
The authors acknowledge Dr. Sizhi Gao for preparation and validation of the P2P-R 1-7600) plasmid construct and Drs. David Lonard and Bert O'Malley for performing selected confirmatory experiments.
The guiding documents for GHI grant applications have evolved to include detailed guidelines on the expected content and the desirable preparation and validation processes.
