Sentence examples for prenatal dose from inspiring English sources
A dose of 0.5 Gy from neon-ion beams induced a marked decrease in breeding activity in the prenatally irradiated male rats, while for the carbon-ion beams or X-rays, the significantly reduced breeding activity was observed only when the prenatal dose was at 1.0 Gy or more.
Post hoc comparisons showed a significant difference between the higher prenatal dose, CPF6, and the vehicle-treated groups (p< 0.01).
Our study showed that a prenatal dose of 900 mg/day of n-3 LCPUFA had no effect on the composite outcome of immunoglobulin E associated allergic disease, comprising eczema or food allergy, in the first year of life.
This suggests that, for compounds with long half-lives, temporary fish advisory-related decreases in daily contaminant intake will not necessarily translate to appreciable decreases in maternal POP body burdens, a highly relevant parameter in determining prenatal dose.
They are worrying about congenital malformations and pediatric cancers, although the prenatal doses their fetuses received in the accident remain far below the threshold for inducing malformation.
Now a report from researchers at the NIEHS indicates that low prenatal doses of BPA in mice may cause potentially carcinogenic alterations in female reproductive tissues [ EHP 117:879–885; Newbold et al.].
Bulky DNA adducts in cord blood reflect the prenatal effective dose to several genotoxic agents including PAHs.
This led to public health concern that prenatal low-dose exposure from fish consumption could adversely affect the fetus.
Kawai et al. (2003) found that prenatal low-dose (2 ng/g and 20 ng/g) BPA exposures were associated with a transient increased aggression score in male rats at 8 weeks of age that resolved at 12 weeks and thereafter.
AVP expression was significantly reduced in male mice at the higher prenatal and postnatal dose.
We previously reported that the prenatal high BPA dose (250 μg/kg BW) resulted in the maximum number of modulated genes (Moral et al. 2008) and proteins (Betancourt et al. 2010) at day 100 compared with day 50; therefore, we focused our mechanism of action studies on mammary glands of rats exposed prenatally to 0 and 250 μg BPA/kg BW at those two ages.
