A number of previous studies have investigated the connections between evolutionary traits and functional properties on the premise that gene functionality impacts on the strength of negative selection.
As a premise of the functional equation method, quasi-static condition is assumed so that the inertial forces of deformation can be neglected [43, 44].
This algorithm identifies the most conserved nucleotide motifs within a set of homologous DNA sequences, under the premise that functional regulatory elements are more highly conserved under natural selection than non-functional DNA sequences [29].
Based on the premise that functional genetic features are most likely to be conserved during evolution, we conclude that AS has only a limited role in functional expansion of the proteome in plants.
Structure-based screens of interactions for specific molecular partners have been devised to accelerate protein interaction discovery, indirectly based on the premise that functional specificity of potential partners is also reflected by their phylogeny.
We noted that chimeras had more than one EFh domain, with 20% having three or four domains, supporting the premise that they are functional.
Systems Toxicology is rooted in the premise that morphological and functional changes in cellular, tissue, organ, and organism levels are caused by, and cause, changes at the genomic, proteomic, and metabolomic level.
As a result, dentistry progressively developed the expertise to restore and rehabilitate dentitions to their original morphology based on an underlying premise that the newly erupted tooth was the ideal functional form.
These functional assessment methodologies rely on the premise that the expressed components of cellular systems are likely to be functionally coordinated and that genes belonging to the same functional unit should show similar expression profiles.
Our approach is based on the premise that the closest paralog is the major determinant of functional compensation.
These include an older wave of U.S. smartphone consumers, as well as in Asia and parts of Europe, coupled with the premise that the mobile web is going to become more sophisticated and functional overall and make apps less important.
