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Taken together, these observations lead us to hypothesize that accumulation of a premature form of CTMP in the inner mitochondrial membrane (due to inhibition of mitochondrial membrane peptidase cleavage) may be responsible for the observed mitochondrial phenotype.
The livers of aged rats displayed increased levels of the premature form of IL-1β as well as increased levels of the activated form of IL-1β (Fig. 3C).
As shown by western blot analysis, using antibodies that recognize both immature and fully mature forms of cathepsin D and cathepsin B, an increased level of the premature form of cathepsin D was detected in U-937 cells after CPTH6 treatment, together with an increase in the heavy chain of the mature enzyme.
Mutations within COL11A1, typically involving the substitution of highly conserved glycine residues or the deletion of whole exons, are responsible for certain forms of Stickler syndrome, a rare and usually dominant Mendelian condition that presents with a severe and premature form of OA manifesting during adolescence [ 7, 8].
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In the design of a composite beam, some of the possible premature forms of failure are listed below: 1. Local buckling Local buckling occurs due to the bending compressive stress.
An excess of differentially regulated non-coding RNAs was found on Chromosome 2 including the intronic antisense RNAs, intergenic RNAs and premature forms of Piwi-interacting RNAs (piRNAs).
Seventy-one clusters were considered to be isoforms or premature forms of other clusters.
Seventy-one clusters were considered to be isoforms or premature forms of other clusters (Additional File 2).
From these, 773 and 178 clusters were considered isoforms or premature forms of other clusters (Additional files 3 and 4).
Initially, premature forms of VEGF-C and VEGF-D are synthesized and subsequently activated when binding to receptors [ 70, 81, 85].
They found an increased likelihood of single ventricular premature contractions (a form of cardiac arrhythmia) after noise peaks.
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