The purpose of this study was to generate low molecular weight Fab and F ab' 2 fragments of the CAIX-targeted chimeric antibody cG250, to compare their CAIX binding affinity to that of intact cG250 and to evaluate their potential as imaging agents in a xenograft tumor model with heterogeneous CAIX expression, as a prelude to using one of these agents for clinical imaging CAIX in hypoxic tumors.
The purpose of the present study was to determine how Link N may influence human mesenchymal stem cell (MSC) differentiation, as a prelude to using Link N and MSC supplementation in unison for optimal repair of the degenerated disc.
The end of the set toyed with classical music, first with "Prelude to John Lewis," using a gentle, dry and Lewislike touch on chords with all their notes carefully articulated, and then with the allegro movement of his "Tribute to Johann Sebastian Bach," a fast swing tune with a fuguelike structure in the theme.
In the present open label trial zonisamide was administered to alcohol dependent subjects to determine its tolerability and its efficacy in reducing ethanol use as a prelude to its use in a large clinical trial.
The latest version of Apple's operating system includes the capacity to automatically toggle between different wireless technologies such as 4G and Wi-Fi which is a prelude to the use of data-encoding technologies that might split up data and use multiple channels at the same time for far more efficient service.
Hence, although we show the data on naïve Tg4 cells in Figures 1 and 3, these really serve as a prelude to the data using Teff cells.
But while the military has been developing and refining options for the White House for months, the discussion appears to have taken a new turn, officials say, in the struggle to determine whether the suspected use of sarin gas near Aleppo and Damascus last month was a prelude to greater use of such weapons.
In conclusion, two in silico approaches and a directed drug screen configured to identify putative drug-gene (mRNA) interactions for rare genetic diseases has provided new putative target drugs that may be further tested for in vivo protein induction as a prelude to potential use as repurposed rare disease therapeutics.
Some human rights monitors, like Amnesty International, have said they believe that Zimbabwe's refusal of further international aid is a prelude to the use of food as a bargaining tool to win support for the governing party in the elections next year.
His discovery in 1819 of the solvent power of hyposulfite of soda on the otherwise insoluble salts of silver was the prelude to its use as a fixing agent in photography; and he invented in 1839, independently of Fox Talbot, the process of photography on sensitized paper.
The feasibility of a full, long term validation of the assay seems favourable and should serve as the prelude to its use in anthrax vaccine research and production in goats.
