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This method is particularly suitable for use in preliminary structure design phase because it is built based on a series of close-formed formulae derived using the simplified analytical method and only a few parameters are needed for calculation.
A preliminary structure activity relationship (SAR) showed that the dihydropyridone scaffold is required for the activity.
The card sorting procedure was performed by the DISABKIDS investigators and assisted in the final item selection and provided a preliminary domain structure for each module for use in the pilot study.
Most of them showed good activity with a broad spectrum and preliminary structure-activity relationship for the substitutions were obtained.
Our analysis establishes a preliminary structure-activity relationship for this class of compounds and reveals a pharmacophore of two aromatic rings, two hydrophobic groups, and one hydrogen-bond acceptor.
Preliminary structure-activity relationships and modeling studies of these new analogues provide valuable avenues for future molecular optimization.
Their bonding partner was identified from preliminary structures.
Brodniansky, have executed preliminary structural proposal for several variations of load-bearing structures.
We also used linear mixed effects models with a compound symmetric covariance structure for preliminary identification of GIS covariates using PROC MIXED in SAS v9.2 (Cary, NC), selecting those that had the lowest (best) AIC or most significant (smallest) p-value in separate models.
Preliminary results of the proposed structure for the integrator application are showed using OPC in Client / Server approach.
A velocity of each layer for the DD method was determined based on the velocity structure for the preliminary location.
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