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Its overall substrate specificity profile, divergent phylogenetic homology, and preliminary pathway analysis suggested potential biological functions for FTT0941c in diverse metabolic degradation pathways in F. tularensis.
Preliminary pathway analysis demonstrated that the data could be useful for hypothesis generation on the pathogenetic mechanisms underlying these two related syndromes.
In addition, we performed a preliminary pathway analysis [12] using these data, to examine the feasibility of this type of tool for future investigations to probe for clues to the pathogenetic mechanisms behind these diseases.
AAP performed preliminary pathway analysis and taught LEO the methodology.
Using pathway enrichment analyses methods similar to those used for pathway analysis in expression microarrays (32), we also conducted preliminary pathway enrichment analyses.
34 In order to achieve maximum model accuracy, proteins escaping previous annotation by KEGG were added to the preliminary pathway setup via sequence analysis and by incorporating data from PlasmoDB.
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Specifically, the preliminary pathways of percolation control the saturation of the residual oil.
It was hypothesized that the preliminary ERAS pathway associated with a beating-heart TECAB procedure could have a synergistic effect on postoperative patient care.
In contrast, the expression of the miR-16 family has been shown to be suppressed >1.5-fold by c-Myc and lin28B in B-cell lymphomas (Chang et al, 2008, 2009), which mirrors the preliminary HBx-c-Myc-miR-15a/16 HBx-c-Myc-miR-15a/16 HBx-c-Myc-miR-15a/16 HBx-c-Myc-miR-15a/16 HBx-c-Myc-miR-15a/16
Although it is particularly challenging to link the different genes, some preliminary disease pathways may already take form.
Current signal analysis methods typically have three steps: build literature based preliminary signaling pathways model; generate gene expression experimental data; detect the shortest path as the specific signal and verify biological meaning.
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