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Because some of the partners have already begun preliminary gene mapping and sequencing, a "rough draft" of the full sequence could be completed by year's end.
We demonstrate how the preliminary gene expression data, coupled with certain realistic assumptions, can be used to estimate the number of immunohistochemical assays required for development.
Efforts are under way to close the remaining gaps; however, the sequence is of sufficient accuracy and contiguity to be declared substantially complete and to support an initial analysis of genome structure and preliminary gene annotation and interpretation.
Preliminary gene array studies indicate that other genes are affected, as well.
Preliminary gene expression profiling experiments from our laboratory suggest that methotrexate-induced expression of multiple growth factors and growth factor receptors could drive activation of PI3K.
That a subset of ERα target genes may require the synthesis of additional cofactor(s) prior to becoming subject to receptor-mediated transcriptional regulation remained a possibility consistent with our preliminary gene expression data.
Using the preliminary gene prediction provided by the Sanger Institute, we performed similarity searches of the deduced amino acid sequences of predicted SL1344 genes not present in LT2 using standalone BLAST V2.2.17 [40].
We remark that IL-6 was not selected by Ray et al. in the preliminary gene selection, and as a consequence it is not part of their 18-protein signature.
We carried out a preliminary gene expression study comparing pooled samples from three SHR and from three WKY rats at 4, 12, 26 and 38 weeks of age [43].
A preliminary gene expression study of two C. elegans strains, daf-2 e1370) daf-2 e1370c17)IV, thandare intrinsically resistant to killing by the fem-1 hc17 IVed fem-1 hc17 IVpression was sthatgly are constintrinsicallyuced in these animals (resistant, unpublished dato).
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In order to accelerate the process of metabolic network reconstruction, the annotated data of the draft genome sequence of S. platensis C1 (NCBI ID 67617) [ 24] were used as the input for the Pathway Tools software version 13.0 [ 26, 27], which can automatically generate a preliminary gene-protein-reaction (GPR) association in the network.
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