Sentence examples for preliminary activity of from inspiring English sources
The design, synthesis and preliminary activity of small molecular weight modulators of the heat shock protein 70 (Hsp70) are described.
We aimed to determine the recommended phase 2 dose, safety, pharmacokinetics, and preliminary activity of tucatinib in combination with capecitabine or trastuzumab in patients with HER2-positive breast cancer with or without brain metastases.
Motivated by findings from preclinical studies showing potent synergistic activity with ricolinostat and lenalidomide, our goal was to assess the safety and preliminary activity of the combination of ricolinostat with lenalidomide and dexamethasone in relapsed or refractory multiple myeloma.
The paper illustrates the preliminary activity of an extensive research program oriented to investigate the multiaxial fatigue behaviour of unidirectional composite laminates, with particular attention to the analysis of the damage mechanisms and their correlation with the local multiaxial stress state to be used then as the basis for the development of multiaxial fatigue criterion.
An additional objective was to explore preliminary activity of this combination.
Furthermore, a recent phase II study found preliminary activity of nab-paclitaxel monotherapy in patients who progressed on gemcitabine-based therapy.
This is a report of the preliminary activities of ISCS Working Group 3. The major objective of our working group is to study the origins and transport of solar emissions through the heliosphere.
Here we described the design, synthesis and preliminary activity studies of novel leucine ureido derivatives as aminopeptidase N (APN/CD13) inhibitors.
Here we described the design, synthesis and preliminary activity studies of novel APN inhibitors with 3-phenylalanyl-N′-substituted-2,6-piperidinedione scaffold.
The aim of this first-in-human phase 1 study was to establish the safety and preliminary activity profile of umbralisib in patients with haematological malignancies.
This preliminary activity requires a sequence of steps: identification of the scenario, in situ inspection, choice of typical configurations (mean and/or worst case), reproduction of the scenario.
