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Further questions related to uncertainty of measurement, pregnancy values, paediatric/adult cut-off, haematology profiles reported and the use of extended parameters.
Postpregnancy A1C was characterized by a larger dispersion, with variance increasing almost four times, compared with pregnancy values.
We created "pregnancy" values for DE, DM, and total DAP concentrations by averaging the two log-transformed pregnancy measures.
It was interesting to note that the pregnancy values were similar to those detected in adults with atherosclerotic diseases [ 16].
We have thus chosen to use the same method of measurement after pregnancy in order to compare directly with pregnancy values despite the limitations of such measurement methodology.
Patients who responded to the 24-28 month survey were invited to attend a special clinic session for repeat BMD measurements to compare with their pregnancy values.
Similar(50)
A marginally loss of BMD was seen when the 2-year post delivery measurement was compared with the early pregnancy value (- 0.022 g/cm, SD 0.04).
A positive gain was seen in all these parameters when the 2-year post delivery measurement was compared with the early pregnancy value (Table 1).
The mean loss in BMD from early to late gestation in the index pregnancy of this cohort was 0.373 g/cm2 (SD 0.029), representing around 5% of the early pregnancy value.
The extent to which this restoration is complete cannot be determined from this study because no pre-pregnancy values were available for the L52 measurement and because the number of women participating was relatively small.
In 17 women with afamin values available also after delivery, afamin concentrations dropped to pre-pregnancy values (median 54.6 mg/l, 25%, 75%-ile 49.1-60.5 mg/l, range 41.8 70.6 mg/l).
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