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Discover LudwigThe phrase "preferred sequencing" is correct and usable in written English, and can be used to refer to the order in which someone would prefer certain events to occur
For example, "We must consider the client's preferred sequencing of tasks when constructing a timeline for the project."
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The resultant effect is a new, constantly changing, and complex treatment paradigm for treating clinicians, who are now required to know the mechanism of actions of new medications, side effect profiles, modes of administration, and preferred sequencing of various treatment options.
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Spo11, like all endonucleases, cleaves preferred sequences.
At rest, preferred sequences of limb movements can be elicited, whereas during locomotion, preferred gait-inhibition patterns are evoked.
Both human and mouse TSSs preferred sequences that are facing towards the histone, hiding their minor groove, hence exposing their major groove.
Surprisingly, footprinting revealed the non- C2 symmetric compounds 2 and 3 also bound DNA sequence 1 quite well, only surpassed by binding to their most highly preferred sequence, DNA sequence 5.
37i This comparison as well as the in vitro versus in vivo results with the Widom 601 sequence cited above illustrate that thermodynamically preferred sequences alone cannot predict nucleosome occupancy within living cells.
Furthermore, using a computational algorithm, we found that Slou-preferred binding sequences are enriched within putative enhancers associated with Slou-responsive genes, suggesting that HD binding to atypical preferred sequences may serve as a general mode of regulation by this TF class.
We therefore analysed the distribution of AID and APOBEC3G preferred sequence context in the yeast genome and find that the densities of AID and APOBEC3G motifs (WRC and YCC respectively) show no enrichment within the highly targeted regions compared to the remaining genome.
When we reason about change over time, causation provides an implicit preference: we prefer sequences of world states in which one world state leads causally to the next, rather than sequences in which one world state follows another at random and without causal connections.
That is why people prefer sequences, like 1234, or patterns, like 8888, Dr. Jones said.
If true, MNase might just prefer sequences which are disfavored by the histone octamer, explaining the high correlation between the profiles obtained by digesting in vitro reconstituted chromatin and naked DNA.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com