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The take-home message for parents: "Whatever parents can do to delay the initiation of alcohol until at least 15 years (or preferentially even older) has the potential of decreasing the risk for later problematic drinking," Kuperman wrote.
Thus, Prx1 appears to be the major isoform encountered by p66Shc and seems to be bound preferentially, even in presence of other peroxiredoxins, indicating a pronounced level of specificity for this interaction.
S. cerevisiae has evolved hierarchical gene regulatory networks (GRNs) that respond to glucose, and these allow glucose to be consumed rapidly and preferentially even when non-glucose sugars are present [ 15– 15].
In addition, there are loci at the single-base resolution that undergo point mutation preferentially even though no simple sequences have been found yet in these loci [ 166- 168].
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Although translation of most mRNAs is attenuated by limiting eIF2α, a subset of mRNAs is preferentially translated even with substantial eIF2α phosphorylation.
Previously, we reported that, when clonal neural stem cells (NSCs) were transplanted into brains of postnatal mice subjected to unilateral hypoxic ischemic (HI) injury (optimally 3 7 days following infarction), donor-derived cells homed preferentially (from even distant locations) to and integrated extensively within the large ischemic areas that spanned the hemisphere.
However, it is possible that one SIM might contribute preferentially or even exclusively to modification of some Pc2 E3 substrates.
Therefore, the current immunotherapeutic concepts focus on targeting those antigens that are preferentially or even exclusively expressed by AML blasts, including the AML stem cell.
When Bcl-2 was overexpressed in CX3CR1-deficient mice, the numbers of Gr1− monocytes was preferentially restored even though both subsets exhibited comparable transgene levels.
Proteins that cycle between endosomes and the plasma membrane in interphase accumulate, preferentially or even exclusively, at the cell plate (Reichardt et al., 2011).
Here de novo assembly was preferentially utilised even though a single willow cultivar was being assessed and the annotated genome sequence for that species (S. purpurea clone 94006) was available.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com