Your English writing platform
Discover LudwigExact(20)
Significant changes were observed for the systems compatibilised with triblock copolymers due to the preferential localisation of the copolymers at the PS/PB interface.
This preferential localisation, termed the 'uterine first-pass effect', was identified because of the marked uterine response to vaginally administered progesterone despite low serum progesterone concentrations [24].
The remaining nuclei either exhibited DMs restricted to the nuclear periphery (10 14%) or a preferential localisation of DMs to nuclear membrane protrusions or micronuclei (<1%).
The mechanism of preferential localisation to the uterus is not clear, although it seems likely that drugs administered via the vagina are absorbed into veins within the upper third of the vagina and then transported by counter-current exchange to the uterine arteries [25], [29], [30].
It thus explains the preferential localisation observed in our bone metastasis models.
We showed that there is a significant preferential localisation of BPRs in small intergenes (Fig. 2).
Similar(40)
Strikingly, γδT cells are ancestral to other lymphoid populations such as αβT cells and B cells, they participate to both innate and adaptive immune responses, have a preferential mucosal localisation and might act as professional antigen-presenting cells [30] recognizing non-peptide antigens found on several pathogens, including mycobacteria, necrotic and tumor cells [31], [32].
On the other side, p53P has a preferential nuclear localisation, as showed by the perfect overlap with Hoechst staining.
A preferential cytoplasmic localisation of Hsp90 was found in the tumours (70%), whereas nuclear staining was detected in only 2.5% of the cases.
In the classical nuclear ER pathway of transcriptional control, the binding of oestradiol to the ER initiates dissociation of heat shock proteins from the ER, followed by receptor dimerisation and preferential nuclear localisation (Beato, 1989; MacGregor and Jordan, 1998).
Although PROSITE scan analysis had identified a potential ER membrane retention signal at the C-terminus of both TRAIL- β and - γ, PSORT II analysis predicted a preferential cytoplasmatic localisation for all TRAIL isoforms (data not shown).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com