Sentence examples for preferential engagement from inspiring English sources

To determine whether and when hippocampal neurons might show preferential engagement for associative vs. nonassociative memory retrieval, we compared time-resolved spike rates for AM+ (associative) vs. HITs and CRs (nonassociative).

Enhanced in vivo potency of anti-HIV-1 bNAbs was associated with preferential engagement of activating, but not inhibitory FcγRs, and Fc domain-engineered bNAb variants with selective binding capacity for activating FcγRs displayed augmented protective activity.

RV treatment remarkably induced the activation of Bak but not Bax, and silencing Bak but not Bax by shRNA almost completely prevented RV-induced cell death, mitochondrial dysfunction and also largely prevented RV-induced AIF release, demonstrating the preferential engagement of Bak but not Bax during RV-induced apoptosis.

Several previous studies involving scene construction have noted the preferential engagement of the right hippocampus (Weiler et al. 2010; Martin et al. 2011; Mullally, Hassabis, and Maguire 2012).

The apparent specificity that accompanies the preferential engagement of an enhancer with a given promoter may therefore rely on their inherent ability to maintain this contact, even temporarily, rather than to establish it.

We hypothesized that the gain of function conferred by the mutant p110α isoform in the LR cells would result in the preferential engagement of the mutant isoform for PI3K signaling under the selective pressure of HER2 inhibition.

Here we sought to determine whether subtype C T/F viruses, which are responsible for the majority of new HIV-1 infections worldwide, share biological properties that increase their transmission fitness, including preferential α4β7 engagement.

Analysis of synergy between PI-103 and BIBW-2992 revealed that cell lines dependent on EGFR/ERBB2-signaling do not benefit from the combination (Fig. 3A, B), which is in line with the network topology suggesting a preferential linear downstream engagement of PI3K signaling downstream of oncogenically activated receptor tyrosine kinases [7], [19].

In summary, we have provided direct evidence, via an ex vivo stable isotope metabolomics approach, for a preferential or primary engagement of DCS with Ddl and therefore suggest a Ddl-centric mechanism of antibiotic action of DCS against M. tuberculosis.

Phagocytosis as a consequence of Fc-receptor engagement can result in preferential presentation of tumour-associated antigens by MHC class-I rather than MHC class-II, potentially activating CD8-positive effector T cells with tumour-antigen specificity (reviewed by Desjarlais et al, 2007).

Angiogenesis, defined by preferential enrichment of VEGFR1 in tumor cells from Golden Retrievers might reflect engagement of unique growth (inhibitory) pathways.