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We predict that inhibition of repair by a drug will trigger preferential death of cancer cells.
This suggests that the preferential death of non-sister spores in the absence of Sgs1 does not result from a Top3-dependent inability to dissolve dHJs.
The preferential death of the nigrostriatal neurons under rotenone exposure may result from the synergic effect of ROS production by complex I inhibition and the presence of dopamine by way of production of oxyradicals and reactive intermediates [30], [31].
The preferential death of cells that failed to arrest in G0/G1 leads to underestimates of the fraction of these cells.
Consistent with this concept, the inactivation of IAPs, especially when combined with other treatments, may result in preferential death of tumour cells, compared with normal cells (36, 39, 40).
The effects of mTECs on the Treg cell phenotype suggest at least four non-mutually exclusive possibilities: higher differentiation of CD25− into CD25+ cells, less death of CD25+ cells, higher proliferation of CD25+ cells, or preferential death of CD25− cells.
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These results for the first time suggest a selective vulnerability of DA neurons towards depletion of anti-oxidant defence, which might be an explanation for their preferential death in PD patients.
This accumulation led to the perturbation of mitochondrial homoeostasis and eventual preferential cell death of the neu-overexpressing cells.
Moreover, although PD symptoms reflect preferential neuronal death, DNA, RNA and biochemical traits of the disease are detectable in blood cells [ 30- 32].
The Death of News Brands.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com