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Five separate preference tasks were administered, requiring subjects to indicate their preference for 12 stimuli presented two at a time, in all possible combinations.
In the current study, rats exposed to variable PNS were evaluated for anxiety-related behaviors in open field, elevated plus maze, and light/dark preference tasks.
Finally, an analysis of visual competency through the use of the visual cliff and light-dark preference tasks indicates that conjugate-injected animals do not suffer any gross defects in visual perception.
One source of validation evidence comes from comparing the outcome of DNMS experiments with those using spontaneous object preference tasks.
Spontaneous preference tasks have been designed to measure memory for object location [15,17], object-in-place information [18], object-in-context conjunctions [18,19], object reconfigurations [20] and object recency [21], but see [2], along with various combinations of these forms of memory [22 24].
The following were described: Recruitment (proportion of people approached who were trained); Participation (a) the proportion of people trained who provided any preferences and (b) the proportion of panel members who contributed to each "set" of values; and Compliance (the proportion, per participant, of preference tasks which were completed).
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Results revealed that stressed animals were highly anxious (Elevated Plus Maze and Open Field), showed depressive-like behavior (sucrose preference task), performed poorly in short-term and long-term associative memory task (passive avoidance step-through task) and displayed reduced locomotion (open field).
Our results show that the protein synthesis inhibition in all of these experimental designs had no effect on conditioned place preference memory under conditions that would initiate reconsolidation, suggesting that if reconsolidation of a conditioned place preference task exists it is not mediated by protein synthesis in basolateral amygdala.
Finally in the third experiment, after habituation and training in the conditioned place preference task, the animals received an injection of the unconditioned stimulus (morphine, i.p.; 7.5 mg/kg) followed by confinement for 10 min in the morphine-paired compartment (conditioned stimulus) during memory retrieval.
Female mate preference may depend on such phenotypic qualities and has been assessed using a four-chamber preference task.
In the current study, when tested during the jet lag treatment, jet-lagged hamsters did not learn the conditioned preference task that control hamsters readily acquired (Figure 3B).
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