The validity of utility preference instruments in women with pelvic organ prolapse has not been established.
Participants rated clinical marker states (CMS) to make respondents familiar with the task of preference instruments, ground their ratings in relation to other health states, and help investigators interpret patient ratings.
Our data collection on subject difficulties with understanding or completing the preference instruments was sparse, limiting our analysis of testing difficulties.
Twenty patients (12%) had difficulty understanding or completing one or more preference assessments; however, there was no association between difficulty understanding or completing preference instruments and cognitive impairment (P = 1.000).
However, generic preference instruments such as the Sickness Impact Profile and Short Form Health Survey-6D were not considered specific enough to detect the asymptomatic nature of glaucoma in its early stages.
In COPD few preference instruments, such as the EQ-5D, the Quality of Well Being Scale (QWB), or the HUI have been used [ 13, 14, 17, 19, 34- 37], some of them with ambiguous results.
This instrument, which we call the Preferences Instrument for Genomic Secondary Results (PIGSR), was designed to allow patients to record their preferences about which secondary or incidental findings they would like to receive.
The investigators used a stated-preference instrument which included all functional domains and symptoms of the EORTC Quality of Life questionnaire (QLQ-C30).
Two qualitative studies will be embedded within the RCT: (1) exercise instructor (clinician) feedback about the exercise preferences instrument (2) participant feedback about their exercise experience.
A qualitative focus group study of exercise instructor feedback about the exercise preferences instrument will be embedded in the research design.
Starting from the second year, though, the magnitude of change in health utility measured by indirect-preference instruments was larger than direct-preference ones.
