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In this context, the QSAR/QSPR model must satisfy two quality standards: high prediction accuracy, preferably evaluated with an external dataset, and good interpretability, evaluated from a physicochemical point of view.
In conclusion, enhanced clinical appreciation of P-wave items on the standard electrocardiogram at rest, preferably evaluated in all 12 leads, may help identify a group at high risk of the development of AF at an early stage.
(1) Effectiveness of interventions is preferably evaluated by randomisation into an intervention and control group.
The effect of a preventive intervention is preferably evaluated in a controlled trial where one or more binary outcomes are monitored continuously during the study period.
Similar(54)
Methodologically good-quality studies, preferably evaluating results with a validated patient-relevant outcome measure such as the KOOS or WOMAC (Paxton and Fithian 2005), are needed to establish the optimal treatment strategy for patients with isolated patellofemoral osteoarthritis.
This new risk model should preferably be evaluated in other cohorts.
For this nonrandomized study design, it may be advisable to treat the breeders as the affected entities or, preferably, to evaluate the dose response data using nested models that account for intralitter correlations, or the tendency of littermates to respond similarly to one another relative to the other litters in a dose group (U.S. EPA 2012a).
After multiple interventions are selected and implemented, their impact on population health risk is evaluated, preferably through measurable indicators of population health improvement.
In order to evaluate the potential benefit of endocrine treatment, hormone receptor status should always be evaluated, preferably in the metastatic sites, but at least in the primary tumor.
Patient-reported outcomes might be evaluated in smaller, preferably randomized studies.
We did not investigate the effects of hip fractures and their treatment on the quality of life as perceived by the patient, as patient-reported outcomes might be better evaluated in smaller, preferably randomised studies.
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