The control group (11 boys, 19 girls) (mean age 12.5 years (SD = 3.1, range 6.0 17.3 years) consisted predominantly of unaffected siblings of the participants with NF1 (n = 22), supplemented with a number of their friends (n = 8).
As TFAM is known to have an influence mtDNA copy numbers [24], we investigated its expression in predominantly affected and unaffected tissues.
MNAR was predominantly localized within the nucleus and was unaffected by Gc treatment (Fig. 6, A and B).
ATP elicited a predominantly transient rise in Ca2+ that was unaffected by removal of extracellular Ca2+ (Fig 2c), showing that ATP acted by evoking Ca2+-release and that Ca2+-stores had not been inadvertently depleted.
Tumor size is relatively unaffected, indicating that this effect acts predominantly at the level of tumor initiation or/and early promotion.
Finally, the sample predominantly comprised participants in the early stages of PD, with relatively unaffected mobility, no treatment-related dyskinesia, no cognitive impairment, high quality of life and who were relatively independent.
Note that the resonances affected by incubation with LDB1-SSDP are predominantly RD-specific (black) whereas most Lip residues (marked by blue) are unaffected.
This pathology diminishes predominantly the expiratory flow, while the filling of the lung during mechanical ventilation may remain unaffected or even increased, explaining why PaO2 was close to normal.
The paper contributes to an empirical literature that relies predominantly on cross-sectional comparisons of child cohorts born before and after the war in war-affected and unaffected regions.
The βPIX morphants showed that at 60% epiboly, E-cadh is predominantly cytoplasmic in both the outer EVL cells and the DEL, again with the junctional actin cytoskeleton remaining relatively unaffected (Figure 6E).
